Read-Gene has unique patent portfolio for DNA testing and chemopreventive pharmaceuticals:
A) 5 international patents granted:
Determining a predisposition to cancer (NBS1) - Patent No. 7,319,007 B2 (USA),
Polymorphism in the human NBS1 gene useful in diagnostic of inherited predisposition to cancer - Patent No. 011608 (Euroazja),
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Patent No. 2006/02081 (RPA),
Determining a predisposition to cancer (CHEK2) - Patent No. 7,407,755 B2 (USA),
Method for determining reduced predisposition to cancer based on genetic profile - Patent 61/069,403 (USA).
B) 6 Polish patents granted:
Mode and test for detection of BRCA1/2 gene mutations in Polish families with aggregation of breast and/or ovarian cancer – PL.185957
Method and test for detection of MSH2/MLH1 gene mutations in Polish families with Lynch syndrome (HNPCC) – PL.192152
Pharmaceutical compositions for food supplementation for people and the mode of its preparation – PL.192139
Method and set designed for detection of high genetic predisposition for prostate gland cancer as well as use of germinal change within the NBS1 gene – PL.201608
Method and set to discover genetic predisposition to colone cancer by using germinal change detector for NOD2 genes – PL.202116
Method and set to discover genetic predisposition to cancer by using germinal change detector for NOD2 genes – PL.202119
C) submission of ten Polish and international patent applications for its genetic cancer discoveries:
Pharmaceutical compositions and methods for the prevention of breast and ovarian cancer – P.361597
Mode and composition of detection of high inherited predisposition to breast and/or ovarian cancer in patients of Polish origin and application of selected mutations within BRCA1 gene – P.364413
Mode and composition for detection of inherited predisposition to various cancers by identification of germline mutation within CHEK2 gene - U.S. Patent Application No. 60/563,089
Mode and composition for detection of inherited predisposition to cancer by identification of germline mutation within NOD2 gene - U.S. Patent Application No. 60/565,724
Polymorphism in the human NBS1 gene useful in diagnostic of inherited predisposition to cancer - PCT/PL04/00044
Polymorphism in the human NBS1 gene useful in diagnostic of inherited predisposition to prostate cancer and lobular invasive breast cancer - National Phase in Ukraine PCT/PL04/000044
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - PCT/PL04/00063
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - EP 04 775 169.8 - 1216 of PCT Application No. PCT/PL2004/000063 - WO2005013951
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - U.S. Serial No. 10/916,025, filed August 10,2004, claiming the benefit of U.S. Serial No. 60/494,239, filed August 11,2003
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Australian Patent Application No. 2004263070
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Canadian Patent Application No. 2,535,506
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Chinese Patent Application No. 200480023124.6
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - India Patent Application No. 533/KOLNP/2006
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Japanese Patent Application No. 2006-523155
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Korean Patent Application No. 10-2006-7002810
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Mexican Patent Application No. PA/A/2006/001632
Pharmaceutical composition and methods for the prevention of breast and ovarian cancer - Patent Application in Ukraine No. a200602525
Determining a predisposition to cancer - PCT/PL2005/00006
Determining a predisposition to cancer - EP 05704666.6-2401
Method, uses and composition for detection of increased or decreased predisposition to various cancers by identification of specific genotypes of CYP1B1 gene - PCT/PL2006/000040
Method, uses and composition for detection of increased or decreased predisposition to various cancers by identification of specific genotypes of CYP1B1 gene - U.S. No. 11/474,160
Method, uses and composition for detection of increased or decreased predisposition to various cancers by identification of specific genotypes of CYP1B1 gene - EP 06769504.9 WO2006137741
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - PCT/PL2007/000035
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - EP 07747744.6
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - Canadian National Phase entry of PCT/PL2007/000035
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - U.S. Serial No. 11/809,574
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - India Patent Application No. 4941/KOLNP/2008
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - National Phase Patent Application in South Africa no. 2008/10173
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - Russian Petent Application No. 2008146886
Fast assignment of adequate neoadjuvant chemotherapy for breast cancer patients based on the identification of constitutional BRCA1 mutations - Australian Patent Application No. 2007268378
Method for determining reduced predispositon to cancer based on genetic profile - PCT/PL2009/000023
Determining a predisposition to cancer by identification of genotype combinations of the genes CYP1B1, BRCA2, CHEK2 - Russian Patent Application
Determining a predisposition to cancer by identification of genotype combinations of the genes CYP1B1, BRCA2, CHEK2 - EP 06748044.7 WO2007148997
Serum selenium level as a diagnostic marker of breast/ ovarian cancer risk in BRCA1 mutation carriers - EP 09461508.5
Fast assignment of adequate chemotherapy with platinum based drugs for cancer patients based on the identification of constitutional BRCA1 mutation - PCT/PL2009/050011
